When CBD is applied topically it is absorbed through the skin's surface to interact with nearby cannabinoid receptors. Nano CBD, however, is a cannabidiol molecule that is coated with tiny particles such as liposomes to stabilize the CBD and move in the bloodstream faster (up to 6X) than “naked” CBD. Heating Nano CBD lotion is made with Capsaicin and Wintergreen. It also contains Nano CBD isolate. This type of Nano CBD lotion is great for muscle aches and pains. This is one of our top selling products because it has multiple ingredients working together to reduce inflammation.